Talking to your healthcare team can determine if AMPYRA^® (dalfampridine) Extended Release Tablets is right for you.

To help them make a more informed decision, you can answer and then discuss a set of questions about how multiple sclerosis (MS) may have been impacting your walking. You can get these questions by downloading the Provider Discussion Guide, a free tool to help you prepare for visits with your healthcare team.

When you talk with your healthcare team about how MS may be affecting your walking and if AMPYRA may be right for you, remember that AMPYRA is not meant to replace your current MS medication. You can take it with your other MS medications or take it alone. Additionally, AMPYRA can be taken by people with any of the major types of MS. Patients with a history of seizure or with kidney problems must not take AMPYRA.

Is there long-term safety information on AMPYRA?

People have been taking AMPYRA for over 5 years as part of continuous safety trials,⁶ and AMPYRA has been evaluated for safety in over 900 people with MS.

Can I take AMPYRA with my current MS medication?

You can take AMPYRA alone or with other MS medications.

Patients were allowed to stay on their current MS medications while in the clinical trials of AMPYRA. Always check with your doctor before taking any new medication. Do not take AMPYRA together with other aminopyridine medications, including compounded 4-aminopyridine (sometimes called 4-AP, fampridine).

Who shouldn't take AMPYRA?

AMPYRA isn't right for everyone. Talk to your doctor about AMPYRA to learn if it is right for you. Do not take AMPYRA if you have ever had a seizure or have certain types of kidney problems. Stop taking AMPYRA and call your doctor right away if you have a seizure.

Taking doses greater than 10 mg twice daily of AMPYRA or drugs with the same active ingredient has been shown to increase the risk of adverse events, including seizures. You won't experience any additional benefits from AMPYRA if you take doses higher than 10 mg twice daily.

Your chance of having a seizure is higher if you take too much AMPYRA or if you have kidney problems. So before taking AMPYRA, tell your doctor if you have kidney problems. Always take AMPYRA exactly as prescribed by your doctor.

Before you take AMPYRA, tell your doctor if you're taking or have been taking compounded 4-aminopyridine (4-AP, fampridine). AMPYRA and compounded 4-AP have the same active ingredient. Discontinue use of any product containing compounded 4-AP before starting treatment with AMPYRA.

What should I tell my doctor before I start taking AMPYRA?

Before you take AMPYRA, tell your doctor if you have any other medical conditions. Tell your doctor about all the medicines you take, including prescription and non-prescription medicines, vitamins and herbal supplements.

Tell your doctor if you are currently taking compounded 4-aminopyridine (fampridine, 4-AP). This has the same active ingredient as AMPYRA. Discontinue use of any product containing compounded 4-AP before starting treatment with AMPYRA.

You must also tell your doctor if you have ever had a seizure or if you have certain types of kidney problems.

Also tell your doctor if you are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your unborn baby. You and your doctor will decide if you should take AMPYRA while you are pregnant.

You should also tell your doctor if you are breast-feeding or plan to breast-feed. It is not known if AMPYRA passes into your breast milk. You and your doctor should decide if you will take AMPYRA or breast-feed. You should not do both.