"Since starting Ampyra, I have the confidence in my ability to do simple things, like keeping up? to meet friends" -Kristie

For Family and Friends

The support of friends and family can be a big source of strength for people who have walking difficulties related to multiple sclerosis (MS). You can help your loved one by trying to better understand the disease, how it may affect their walking, and how AMPYRA® (dalfampridine) may help.

Here are some ways to lend support:

  • Start simple — tell your loved one that you want the best for them, and that you have questions about their walking. They might be waiting for an opportunity to admit they have concerns
  • Encourage your loved one to fill out a discussion guide before meeting with their healthcare team to help them prepare for their visit
  • Ask if your loved one will take a walking self-assessment, then have them share it with their healthcare team
  • Ask how to support your loved one in their relationship with their healthcare team
  • Be an active listener in support of your loved one's needs and goals

MS affects people's walking in different ways

It's important to understand how MS affects your loved one’s ability to walk. Recognizing their symptoms, how they start up, how often they occur, and if they are getting better or worse can all play key roles in helping their healthcare team decide if they should try AMPYRA. It’s also important to know whether they have a history of seizures or have kidney problems or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA, since people with these conditions must not take AMPYRA.

AMPYRA® (dalfampridine) is indicated as a treatment to improve walking in patients with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.


Do not take AMPYRA if you
  • have ever had a seizure,
  • have certain types of kidney problems, or
  • are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.

Take AMPYRA exactly as prescribed by your doctor.

Before taking AMPYRA, tell your doctor if you
  • have kidney problems or any other medical conditions
  • are taking compounded 4-aminopyridine
  • are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your unborn baby.
  • are breast-feeding or plan to breast-feed. It is not known if AMPYRA passes into your breast milk. You and your doctor should decide if you will take AMPYRA or breast-feed. You should not do both.
  • are taking any other medicines

Stop taking AMPYRA and call your doctor right away if you have a seizure while taking AMPYRA. You could have a seizure even if you never had a seizure before. Your chance of having a seizure is higher if you take too much AMPYRA or if your kidneys have a mild decrease of function, which is common after age 50. Your doctor may do a blood test to check how well your kidneys are working before you start AMPYRA.

AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.

AMPYRA may cause serious side effects, including
  • severe allergic reactions. Stop taking AMPYRA and call your doctor right away or get emergency medical help if you have shortness of breath or trouble breathing, swelling of your throat or tongue, or hives;
  • kidney or bladder infections.

The most common adverse events for AMPYRA in MS patients were urinary tract infection, trouble sleeping, dizziness, headache, nausea, weakness, back pain, and problems with balance.

Please see Patient Medication Guide for complete safety information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

AMPYRA®, ACORDA THERAPEUTICS® and the stylized ACORDA THERAPEUTICS® logo are registered trademarks of Acorda Therapeutics, Inc. | AMPYRA® is marketed by Acorda Therapeutics, Inc. and manufactured under license from Alkermes Pharma Ireland Limited (APIL), Ireland. | AMPYRACONNECT™ is a trademark of Acorda Therapeutics, Inc. | The stylized path logo and the stylized Acorda logo are trademarks of Acorda Therapeutics, Inc. | © 2014 Acorda Therapeutics, Inc. All rights reserved.

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