Do's and Don'ts of Dosing
Now that you're trying to improve your walking with AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, remember:
- Take AMPYRA exactly as your doctor tells you to take it. Take one tablet of AMPYRA two times each day about 12 hours apart.
- Do not take more than two tablets of AMPYRA in a 24-hour period. If you miss a dose of AMPYRA, do not double up on your medication. Wait until your next regularly scheduled dose instead.
- Take AMPYRA tablets whole. Do not break, crush, chew or dissolve AMPYRA tablets. If you cannot swallow AMPYRA tablets whole, tell your doctor. AMPYRA is released slowly over time. If the tablet is broken, the medicine may be released too quickly.
- AMPYRA can be taken with or without food.
Do not take AMPYRA if you have ever had a seizure, have certain types of kidney problems, or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA. AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.
More dosing questions about AMPYRA? Ask your doctor or call the AMPYRA patient hotline toll-free at 1-888-881-1918.
Indication
AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the first and only brand prescription medicine indicated to help improve walking in adults with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.
Important Safety Information
Do not take AMPYRA if you have ever had a seizure, have certain types of kidney problems, or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.
Indication & Important Safety Information
INDICATION
AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the first and only brand prescription medicine indicated to help improve walking in adults with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.
IMPORTANT SAFETY INFORMATION
Do not take AMPYRA if you:
- have ever had a seizure,
- have certain types of kidney problems, or
- are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.
Take AMPYRA exactly as prescribed by your doctor.
Before taking AMPYRA, tell your doctor if you:
- have any other medical conditions
- are taking compounded 4-aminopyridine
- are taking any other prescription or OTC medicines, such as cimetidine
- are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your unborn baby.
- are breastfeeding or plan to breastfeed. It is not known if AMPYRA passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby if you take AMPYRA.
Stop taking AMPYRA and call your doctor right away if you have a seizure while taking AMPYRA. You could have a seizure even if you never had a seizure before. Your chance of having a seizure is higher if you take too much AMPYRA or if your kidneys have a mild decrease of function, which is common after age 50. Your doctor may do a blood test to check how well your kidneys are working before you start AMPYRA.
AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.
AMPYRA may cause dizziness or vertigo. If you have these symptoms do not drive, operate machinery or do other dangerous activities.
AMPYRA may cause serious side effects, including severe allergic reactions. Stop taking AMPYRA and call your doctor right away or get emergency medical help if you have shortness of breath or trouble breathing, swelling of your throat or tongue, or hives.
The most common side effects for AMPYRA in MS patients were urinary tract infection; trouble sleeping; dizziness; headache; nausea; weakness; back pain; problems with balance; multiple sclerosis relapse; burning, tingling, or itching of your skin; irritation in your nose and throat; constipation; indigestion; and pain in your throat.
Please see the Patient Medication Guide.
