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How to Get Started on AMPYRA® (dalfampridine)

We're here to make getting started on AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, as simple as possible by providing tools and resources to help.

How to start the conversation with your doctor

You may find it hard to accept your MS-related walking difficulties at first. And just as hard to discuss them with your doctor.

That's why we've provided this helpful doctor's discussion guide.

Download your Doctor Discussion Guide now.

A FREE* trial to see if AMPYRA is right for you

Wanting to walk better is a good reason to ask your doctor about AMPYRA and the FREE* trial at your next visit. While AMPYRA does not work for everyone, the AMPYRA FREE* trial is a no-cost way to see if it works for you.

Learn more about the AMPYRA FREE* trial.

*Limitations and restrictions apply.

Assistance with AMPYRA insurance coverage

If you are prescribed AMPYRA, AMPYRA Patient Support Services (APSS) can confirm whether your insurance will cover your prescription, and whether you are eligible for our co-pay program.

Once you make a commitment to trying AMPYRA, it is our commitment to assist you along the way.

Find out how APSS can assist you.

AMPYRA support and benefits

We have created a support program for people with MS who take AMPYRA and their care partners. This free program is designed to inform, educate, and motivate you throughout your experience with AMPYRA.

You also have a unique opportunity to participate in a Survey designed to help you talk about changes in your walking with your doctor.

Learn more about AMPYRA support.

Realizing you have walking difficulty is a step in the right direction.

Indication

AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the only prescription medicine indicated to help improve walking in adults with MS. This was demonstrated by an increase in walking speed.

Important Safety Information

Do not take AMPYRA if you have ever had a seizure, have certain types of kidney problems, or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.

Indication & Important Safety Information

AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the only prescription medicine indicated to help improve walking in adults with MS. This was demonstrated by an increase in walking speed.

IMPORTANT SAFETY INFORMATION

Do not take AMPYRA if you

  • have ever had a seizure,
  • have certain types of kidney problems, or
  • are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.

Take AMPYRA exactly as prescribed by your doctor.

Before taking AMPYRA, tell your doctor if you

  • have kidney problems or any other medical conditions
  • are taking compounded 4-aminopyridine
  • are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your unborn baby.
  • are breast-feeding or plan to breast-feed. It is not known if AMPYRA passes into your breast milk. You and your doctor should decide if you will take AMPYRA or breast-feed. You should not do both.
  • are taking any other medicines

Stop taking AMPYRA and call your doctor right away if you have a seizure while taking AMPYRA. You could have a seizure even if you never had a seizure before. Your chance of having a seizure is higher if you take too much AMPYRA or if your kidneys have a mild decrease of function, which is common after age 50. Your doctor may do a blood test to check how well your kidneys are working before you start AMPYRA.

AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.

AMPYRA may cause serious side effects, including

  • severe allergic reactions. Stop taking AMPYRA and call your doctor right away or get emergency medical help if you have shortness of breath or trouble breathing, swelling of your throat or tongue, or hives;
  • kidney or bladder infections.

The most common adverse events for AMPYRA in MS patients were urinary tract infection, trouble sleeping, dizziness, headache, nausea, weakness, back pain, problems with balance, multiple sclerosis relapse, burning, tingling, or itching of your skin, irritation in your nose and throat, constipation, indigestion, and pain in your throat.

Please see Patient Medication Guide for additional safety information.

You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

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