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How to Get Started on AMPYRA® (dalfampridine)

We're here to make getting started on AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, as simple as possible by providing tools and resources to help.

How to start the conversation with your doctor

You may find it hard to accept your MS-related walking difficulties at first. And just as hard to discuss them with your doctor.

That's why we've provided this helpful doctor's discussion guide.

Download your Doctor Discussion Guide now.

See if you are eligible for a $0 co-pay*

If you have commercial insurance (employer-sponsored or individual), you may be eligible for co-pay assistance where allowed by law. This co-pay assistance may lower the amount you pay for your AMPYRA prescription to as little as $0 per monthly prescription.

Find out about $0 co-pay* for AMPYRA.

*Limitations and restrictions apply.

Assistance with AMPYRA insurance coverage

If you are prescribed AMPYRA, MyAmpyra can confirm whether your insurance will cover your prescription and whether you are eligible for our co-pay program.

Once you make a commitment to trying AMPYRA, it is our commitment to assist you along the way.

Find out how MyAmpyra can assist you.

AMPYRA support and benefits

We have created a support program for people with MS who take AMPYRA and their care partners. This free program is designed to inform, educate, and motivate you throughout your experience with AMPYRA.

You also have a unique opportunity to participate in a Survey designed to help you talk about changes in your walking with your doctor.

Learn more about AMPYRA support.

Realizing you have walking difficulty is a step in the right direction.

Indication

AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the first and only brand prescription medicine indicated to help improve walking in adults with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.

Important Safety Information

Do not take AMPYRA if you have ever had a seizure, have certain types of kidney problems, or are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.

Indication & Important Safety Information

INDICATION

AMPYRA® (dalfampridine) Extended Release Tablets, 10 mg, is the first and only brand prescription medicine indicated to help improve walking in adults with multiple sclerosis (MS). This was demonstrated by an increase in walking speed.

IMPORTANT SAFETY INFORMATION

Do not take AMPYRA if you:

  • have ever had a seizure,
  • have certain types of kidney problems, or
  • are allergic to dalfampridine (4-aminopyridine), the active ingredient in AMPYRA.

Take AMPYRA exactly as prescribed by your doctor.

Before taking AMPYRA, tell your doctor if you:

  • have any other medical conditions
  • are taking compounded 4-aminopyridine
  • are taking any other prescription or OTC medicines, such as cimetidine
  • are pregnant or plan to become pregnant. It is not known if AMPYRA will harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if AMPYRA passes into your breast milk. Talk with your healthcare provider about the best way to feed your baby if you take AMPYRA.

Stop taking AMPYRA and call your doctor right away if you have a seizure while taking AMPYRA. You could have a seizure even if you never had a seizure before. Your chance of having a seizure is higher if you take too much AMPYRA or if your kidneys have a mild decrease of function, which is common after age 50. Your doctor may do a blood test to check how well your kidneys are working before you start AMPYRA.

AMPYRA should not be taken with other forms of 4-aminopyridine (4-AP, fampridine), since the active ingredient is the same.

AMPYRA may cause dizziness or vertigo. If you have these symptoms do not drive, operate machinery or do other dangerous activities.

AMPYRA may cause serious side effects, including severe allergic reactions. Stop taking AMPYRA and call your doctor right away or get emergency medical help if you have shortness of breath or trouble breathing, swelling of your throat or tongue, or hives.

The most common side effects for AMPYRA in MS patients were urinary tract infection; trouble sleeping; dizziness; headache; nausea; weakness; back pain; problems with balance; multiple sclerosis relapse; burning, tingling, or itching of your skin; irritation in your nose and throat; constipation; indigestion; and pain in your throat.

Please see the Patient Medication Guide.

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